Apologies to Bill Cosby. One of my patients was wheeled into the SICU this afternoon still quite groggy from the anesthesia. Midazolam, which had been given to this patient, acts on the same receptors in the brain that alcohol does, and some of the effects are therefore similar. The effects we want are the amnesia and the sedation, so patients don't remember what happened, and they are pretty sleepy, even without the more powerful drugs that knock them out. But after those drugs have worn off, the effects of the midazolam often linger. And the side effect which makes this humorous is the disinhibition.
So, as Mr. Smith was being settled into the ICU, accompanied by his lovely wife, I asked him if there was anything I could get for him. In a sleepy but still forceful voice, he shot back "a bevy of blondes and a coffee."
It's a pity he was NPO. I couldn't even help him out halfway.